In the mid-22nd century, the Earth ship Enterprise is launched under the command of Captain Jonathan Archer. When the crew rescues an alien from a crashed spaceship, Earth gets its first look at the alien's race - the Klingons. Archer and his crew must walk a fine line as they attempt to communicate with the Klingon pilot, whose language is completely unknown, and whose homeworld wants him back. Is this the beginning of friendship...or interstellar war?

Captain Archer wants to convert curiosity into deeds and decides to enter a ship floating in space. Hoshi has trouble adjusting to life on Enterprise.

Archer sends an away team to a habitable, luscious planet for observation. But when a storm occurs, the team begins to experience paranoid delusions.

After helping to repair the warp drive on board of a Xyrillian ship, Trip notices a strange bulging on his arm.

Enterprise tries to find out what happened on Terra Nova, the first colonization attempt outside Earth's solar system.

Archer, Trip and T'Pol are captured by the Andorians at a Vulcan monastery on P'Jem. They believe that the monastery is being used to spy on Andoria.

Enterprise discovers a comet which contains the very rare element eisilium. Then unexpectedly a Vulcan ship arrives. Captain Vanik tells they're interested in human behavior.

T'Pol finds unusual neutrino readings on a planet with a preindustrial society.

Enterprise is sent to help the freighter Fortunate after an attack. However, its first officer, Ryan, is hiding something.

Enterprise has a group of aliens watching a stellar phenomenon on board. When the ship is miraculously saved from blowing up, crewman Daniels has an important message for Archer.

After an attack by a mysterious ship, Archers orders Enterprise's return to Jupiter to install phase cannons; Hoshi makes plans for Malcolm's birthday.

Phlox is asked to save the Valakians from annihilation by disease. However, he discovers something unusual about the Menk, another humanoid race on the planet.

Enterprise tries to rescue a Klingon ship from sinking into a gas giant.

T'Pol is being recalled because of Enterprise's involvement in the destruction of the P'Jem sanctuary. She and Captain Archer are later kidnapped while visiting the planet Coridan.

While returning to Enterprise in Shuttlepod One, Trip and Reed see apparent evidence that the ship has been destroyed. With only days of oxygen left, they must find a way to survive long enough for rescue.

When Enterprise encounters a ship of Vulcan pilgrims, T'Pol is convinced by one of them to perform a Vulcan mind meld.

Archer has visions of a mysterious humanoid woman on a rogue planet where it is eternally nighttime.

Almost the entire crew is left unconscious when four Ferengi pirates raid Enterprise. A still conscious Trip is the only one who can get rid of them.

The crew of Enterprise searches for a seemingly abandoned ship on a desert planet.

Archer and Mayweather are captured by the Tandarans and placed in a Suliban internment camp.

A fibrous, web-like alien creature comes aboard the ship and several of the crew becomes entangled in it including Archer and Trip, and it seems Hoshi is the only one who can try to communicate with the creature.

Enterprise is planning a trip to the relaxation planet Risa, when it gets an urgent request from the Vulcan High Command. They must pick up ambassador V'Lar who has fallen in disgrace. Apparently she misused her position during negotiations on the planet Mazar and has been evicted. After Enterprise picked up V'Lar and is on its way for a meeting with the Vulcan warship Sh'Ran, suddenly a Mazarite ship appears. They want V'Lar for further interrogating. When captain Archer wants to discuss it first with Starfleet Command, they open fire.

Enterprise is for the second time on its way to Risa when yet again another urgent matter comes up: a distress call. It comes from a small vessel. The owner, Zobral, is extremely happy with the help from Enterprise and invites Captain Archer to his home world for a good meal and a game of Geskana. When Archer and Trip have landed on the desert planet, Enterprise gets a message from the Torothan Chancellor Trelit. He says Zobral isn't as nice a man as captain Archer thinks.

The members of the Enterprise crew are faced with various misadventures and challenges while taking a two day break from their duties on the planet of Risa.

After apparently causing the destruction of an alien colony, the Enterprise is called back to Earth. Archer learns via Daniels that the Suliban are trying to sabotage Enterprise's mission.